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Ferentis’ primary commercial focus is hydrogel products and kits for in vitro cell and tissue culture applications.  We will also assist our clients in custom-design of biomimetic materials as templates for stimulating regeneration of target tissues and organs for potential clinical application.

Our target customers are scientific institutions, biopharma and the consumer products industry. Our products provide innovative solutions for professionals who are working in the fields of cell research, regenerative medicine, testing and production of drugs, cosmetic and other bioactive products.





Balion, Z., Svirskienė, N., Svirskis, G., Inokaitis, H., Cėpla, V., Ulčinas, A., Jelinskas T., Eimont R., Paužienė, N., Valiokas, R., Jekabsone, A. 
Comparison of Microglial Morphology and Function in Primary Cerebellar Cell Cultures on Collagen and Collagen-Mimetic Hydrogels. Biomedicines, April 2022, 10(5):1023.

Miksiunas, R., Aldonyte, R.Vailionyte, A.Jelinskas, T.Eimont, R.Stankeviciene, G.Cepla, V.Valiokas, R., Rucinskas, K., Janusauskas, V., Labeit, S., Bironaite, D. 
Van Acker, S.I., Van den Bogerd, B., Van Acker, Z.P., Vailionytė, A., Haagdorens, M., Koppen, C., Ní Dhubhghaill, S., Dartt, D.A., Pintelon, I.
Characterisation of Gel-Forming Mucins Produced In Vivo and In Ex Vivo Conjunctival Explant Cultures. 
International Journal of Molecular Sciences. 2021; 22(19):10528.
Žiniauskaitė A, Cėpla VJelinskas TEimont R, Ulčinas A, Aldonytė RValiokas R, Kalesnykas G, Hakkarainen JJ. (2021)
Introducing an Efficient In Vitro Cornea Mimetic Model for Testing Drug Permeability. 
Sci. 2021; 3(3):30. DOI:
Balion Z., Cėpla V., Svirskiene N., Svirskis G., Druceikaitė K., Inokaitis H., Rusteikaitė J., Masilionis I., Stankevičienė G., Jelinskas T., Ulčinas A., Samanta A., Valiokas R., Jekabsone A. (2020)
Biomolecules. 2020; 10(5):754. DOI:
Balion Z., Sipailaite E., Stasyte G., Vailionyte A., Mazetyte-Godiene A., Seskeviciute I., Bernotiene R., Phopase J., Jekabsone A. (2020)
Investigation of Cancer Cell Migration and Proliferation on Synthetic Extracellular Matrix Peptide Hydrogels
Frontiers in Bioengineering and Biotechnology. DOI: 10.3389/fbioe.2020.00773
Mölzer C., Shankar S.P.,  Griffith M., Islam M. M., Forrester J.V., Kuffová L. (2019)
Activation Of Dendritic Cells By Crosslinked Collagen Hydrogels (Artificial Corneas) Varies With Their Composition
Tissue Engineering and Regenerative Medicine. DOI: 10.1002/term.2903 
Haagdorens M., Cėpla V., Melsbach E., Koivusalo L., Skottman H., Griffith M., Valiokas R., Zakaria N., Pintelon I., Tassignon M. (2019)
In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds
Stem Cells International. DOI: 10.1155/2019/7867613
Samarawickrama C, Samanta A, Liszka A, Fagerholm P, Buznyk O, Griffith M, Allan B. (2018)
Collagen-Based Fillers as Alternatives to Cyanoacrylate Glue for the Sealing of Large Corneal Perforations.
Cornea. 37(5):609–616, MAY 2018. DOI: 10.1097/ICO.0000000000001459 
Jangamreddy, J. R., Haagdorens M. K. C., Islam, M., Lewis, P., Samanta, A., Fagerholm, P., Liszka, A., Ljunggren, M. K., Buznyk, O., Alarcon, E. I., Zakaria, N., Meek, K. M., Griffith, M.  (2018)
Acta Biomaterialia, 2018. DOI: 10.1016/j.actbio.2018.01.011
Islam, M., Ravichandran, R., Olsen, D., Ljunggren, M. K., Fagerholm, P., Lee, C.J., Griffith, M., Phopase, J. (2016)
RSC Adv., 2016. DOI: 10.1039/C6RA08895C
Ravichandran, R., Islam, M., M., Alarcon, E., I., Samanta, A., Wang, S., Lundström, P., Hilborn, J., 
Griffith, M., Phopase, J. (2016)
Functionalised type-I collagen as a hydrogel building block for bio-orthogonal tissue engineering applications.
Mater. Chem. B. 4: 318-326
Ravichandran, R., Griffith, M., Phopase, J. (2014) 
Applications of self-assembling peptide scaffolds in regenerative medicine: the way to the clinic.
J. Mater. Chem. B. 2: 8466-8478
Islam, M., Cėpla, V., Hec Cn, Edind J., Rakickas T., Kobuche K., Ruželė Ž., Jackson B.W., Rafat, M., Lohmanne C.P., Valiokas R., Griffith, M. (2014)
Functional fabrication of recombinant human collagen–phosphorylcholine hydrogels for regenerative medicine applications.
Acta Biomaterialia.
Vignoni, M., Weerasekera, H.dA., Simpson, M.J., Phopase, J., Mah, T.F., Griffith, M.,* Alarcon, E.I.,* and Scaiano, J.C.* (2014)
LL37 peptide@silver nanoparticles: Combining the best of the two worlds for skin infection control.
Nanoscale, 6: 5725-5728 (*equal contribution).
Koh LB, Islam, MM, Mitra D, Noel CW, Merrett K, Odorcic S, Fagerholm P, Jackson WB, Liedberg B,
Phopase P, Griffith M. (2013)
Epoxy cross-lnked collagen and collagen-laminin peptide hydrogels as corneal substitutes.
J Funct Biomater. 4: 162-177.
KhanFA, Rabong C, Jordis U, Phopase J. (2013)
Surprising behavior of NXO-peptides toward the lithium hydroxide solvolysis
Tetrahedron Letters 54: 3679-3682. 
Rakickas T., Ericsson E. M., Ruželė Ž., Liedberg B., Valiokas R. (2011)
Functional Hydrogel Density Patterns Fabricated by Dip-Pen Nanolithography and Photografting,
Small, 15, 2153–2157.
Fagerholm P, Lagali NS, Merrett K, Jackson WB, Munger R, Liu Y, Polarek JW, Söderqvist M,  Griffith, M. (2010) A biosynthetic alternative to human donor tissue for inducing corneal regeneration: 24 month follow-up of a Phase I clinical study.
Science Transl. Med. 2: 46ra61.
Rabong C, Jordis U, Phopase J. (2010) 
NXO-building blocks for backbone modification of peptides and preparation of pseudopeptides

J. Org. Chem. 75: 2492-2500.
Deng,C., Zhang, P., Vulesevic, B., Kuraitis, D., Li, F., Yang, A.F., Griffith, M., Ruel, M. and Suuronen, E.J. (2010)
A Collagen-Chitosan Hydrogel for Endothelial Differentiation and Angiogenesis.
Tissue Eng. 16: 3099-3109.
Dare, E.V., Griffith, M., Poitras, P, Wang, T., D.J., Dervin, G.F., Giulivi, A. and Hincke, M.T. (2009) 
Fibrin sealants from fresh or fresh/frozen plasma as scaffolds for in vitro articular cartilage regeneration
Tissue Engineering Part A, 15: 2285-2297.
Phopase, J.; Jordis, U. (2008)
NXO-modified amino acids: Novel building blocks for peptidomimetics
A Chimica Oggi - Chemistry Today, 2008, 26, 53.
Liu Y, Gan L, Carlsson DJ, Fagerholm P, Lagali N, Watsky MA, Munger R, Hodge WG, Priest D, Griffith M. (2006).
A simple, cross-linked collagen tissue substitute for corneal implantation
Invest.Ophthalmol. Vis. Sci. 47:1869-1875.
Suuronen, E.J., Veinot, J.P., Wong, S., Kapila, V., Price, J., Griffith, M., Mesana, T.G. and Ruel M. (2006).
Tissue engineered injectable collagen-based matrices for improved cell delivery and vascularization of ischemic tissue using CD133+ progenitors expanded from the peripheral blood
Circulation 114: 138-144. 
Li, F., Carlsson, D.J., Lohmann, C.P., Suuronen, E.J., Vascotto, S., Kobuch, K., Sheardown, H., Munger, R, Griffith, M. (2003)
Cellular and nerve regeneration within a biosynthetic extracellular matrix: corneal implantation

Proc. Natl. Acad. Sci USA 100: 15346-15351. 
Jordis, Ulrich; Phopase, Jaywant B.,
Preparation of modified amino acids, especially N-oxalyl amino acid hydrazides, and their use as building blocks for peptide and amino acid mimetics and analogs
WO 2007095980.

































Griffith, M., Osborne, R., Munger, R., Xiong, X., Doillon, C.J., Laycock, N.L., Hakim, M,. Song, Y. and Watsky, M.A.(1999)
Functional human corneal equivalents constructed from cell lines
Science 286: 2169-2172. 





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